Research Assistant / Associate in Bioinformatics and Chromatin biology (Maternity Cover)

During this position, the post-holder will work on the epigenetic and enhancer-related mechanisms regulated by chromatin proteins identified from our CRISPR screen and RNA-seq analysis, to regulate/associate with noncoding RNA expression leading to mRNA regulation. We are examining the global changes in transcription and enhancer activity regulated by these chromatin proteins and define the role of them in transcriptional regulation in human breast cancer cell lines. A large part of the work by the candidate will be in analysing KAS-seq, ChIP-seq, ATAC-seq, bulk and single cell RNA-seq datasets generated on the Illumina next generation sequencing platform in an integrative manner to understand the specific role of the epigenetic proteins in mRNA regulation.

• Hold (or expect to hold shortly) a Masters or PhD (or equivalent) in Bioinformatics/Molecular Biology


• Have advanced Bioinformatics training, at least to Masters level or ideally to PhD level.


• Have excellent computing skills, specifically experience of programming in one or more of Python, R, Perl, Java or C\C++


Desirable Skills

• Training in statistics or mathematics


• High-throughput sequencing data analysis (e.g. RNA-Seq and ChIP-Seq data)


• High Performance Computing (e.g. Ethernet clusters)


• Publishing computational methods as open source software


• Software development using version control (e.g. GitHub, SVN etc.)
  
  What you will get in return:


• Fantastic market leading Pension scheme


• Excellent employee health and wellbeing services including an Employee Assistance Programme


• Exceptional starting annual leave entitlement, plus bank holidays


• Additional paid closure over the Christmas period


• Local and national discounts at a range of major retailers


As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working you can find out more here

Hybrid working arrangements may be considered.